Dr Amy Hughes

Oncology & Hematology


Dr. Amy Hughes is board certified in medical oncology and internal medicine; and holds a bachelor’s degree in psychology. Dr. Hughes graduated magna cum laude from Albion College with a degree in psychology. She received her medical training at Des Moines University, followed by an internal medicine residency at Iowa Health Systems in Des Moines and a fellowship at the Henry Ford Hospital in Detroit, MI. She joined Medical Oncology & Hematology Associates of Iowa in 2012. In October 2018, Dr. Hughes also became a member of Knoxville Hospital & Clinics medical staff.

Dr. Hughes is a member of the American Medical Association, American Osteopathic Association, Iowa Osteopathic Medical Association, American College of Physicians, American Society of Clinical Oncology, American Society of Hematology, Christian Medical and Dental Association

To make an appointment to see Dr. Hughes in Knoxville, call 641-842-7211. She sees patients in Knoxville on the 1st and 3rd Tuesday of the month. 


  • Henry Ford Hospital, Wayne State University, Detroit, MI, Fellowship, Hematology/Oncology


  • Central Iowa Health System-Methodist, Des Moines, IA, Residency, Internal Medicine

Medical School

  • Des Moines University-College of Osteopathic Medicine, Medical School


  • Albion College, BA, Psychology, magna cum laude, Undergraduate

Certifications & Licensure

  • American Board of Internal Medicine, certified in internal medicine
  • American Board of Internal Medicine, certified in medical oncology
  • IA Medical License
  • Michigan State Medical License


  • Medical Oncology, Hematology, Internal Medicine

Professional Affiliations

  • American Medical Association
  • American Osteopathic Association
  • Iowa Osteopathic Medical Association
  • American College of Physicians
  • American Society of Clinical Oncology
  • American Society of Hematology
  • Christian Medical and Dental Association

Awards, Honors & Recognition

  • CMS Stage 1 EHR, 2012
  • CMS Stage 1 EHR, 2013